The LIQUID (LIfecourse QUantification of Inflammation and carDiometabolic health) Study: relationships between inflammatory markers and preclinical cardiometabolic phenotypes across the life course in an international multi-cohort study

Inflammation is key to the development of cardiovascular and metabolic (cardiometabolic) diseases. However, it is largely unknown how inflammation markers relate to early measures of cardiometabolic risk, especially in children. Using existing data collected by large international cohorts from infancy to old age, we will investigate the cross-sectional relationship between inflammation markers, metabolic health, and pre-clinical cardiovascular phenotypes at different stages of life. Data collected in childhood as part of the Born in Bradford study will be an important addition to LIQUID.